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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354d87b6308573f58b4933202a113701fae0b1cdc6df92fa06a3c7ce892f9a6c' 
  AND token = '51RNdMPyDG+BcA7/K2olQh+wAe+7blNm+iY2TasKV1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}