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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d151e29e805242e11351840bd512ee8aff5b71dc5a4812a298c9a72a5b8580c' 
  AND token = 'HjMfWJ9SzYU2Fg3yFSZsAfiioQ+9vqaLfESUNGjQv5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}