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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053ba08fb2f1d537cf9a6a3d52c3f5e78a413b2113d715edacd247386b2bfe56' 
  AND token = 'SiOqzBc0JaUc5lNmxh2yFRA4KuQP43WV8ZJzut4NOYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}