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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2821aa0261f1dd1a727256cea87aad353c8828bf39c196909d29dd1150b1ba37' 
  AND token = 'j+PUqaoCLMFxrAsxvV5XX20JpGadWUwAvUc1mt8qXkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}