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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08aeb4fa57e3dd3d3c965df1e0e81c868138880c94f58cf6fee55338c23fd01e' 
  AND token = 'v2aRoE1IrXYjFwkr/gpRQ/vZmOmgDP21pu23JD6hzy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}