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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e7f8582ec3d8af277c3e4923963484370eb44ec40f54cb17595f705c3c070b' 
  AND token = 'e6+e7qBk3IdY6lXUrUAgP/R4js97ZH4YJMttmQWGOH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}