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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3f721c1f007abb4aa6308d4c2b0fc3739dd4a4143f3c4da23c6cf9f0ea18b1' 
  AND token = 'thTf3sOHgMDm9hvfY81mCWfbPFKgHH8dZJvRZ0GWshY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}