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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ae405e51c50672e39371c2ad54811707fb35b497f94a0f5f9110bc1425e457' 
  AND token = 'pHmdfJi1CCXd96SuZRz77H6nK+HagX/Vs7s3TzuWZmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}