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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9666af364c8a4564d6d90d2b15509981109b521a4181b8da56f26869a69b480c' 
  AND token = 'bXAvs0ws8HCVytspq7FkctfoP7KRZKZD2/FLhdIJW6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}