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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad68c4fb0a76a23c616241985dccbe8d27e38e57a4bb88261363bb08d38f1f1' 
  AND token = 'XuGZVJjUqQi+QST5naDtyw8s4hOX+TBuadf+gDfZiek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}