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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff22495a633115a934fe9deb09309e92bb5a914c204ae7646dbac9e6a4908d9' 
  AND token = 'eP7D0SLvSq0MYG7QnovvdaC+uBNug+PhoSo0kQdQKlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}