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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce36d7cdec349e25ba673b39ed1aeea0d86f0dce85b224c02bae992ab2b69a6c' 
  AND token = 'p2Ppcb8SfL30rLFC4f+Exojb7Ig88QOOgY3LRPSerlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}