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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adf63cc29a26d9b3e27b698417bf0a6d05435c012e785116aae7c35c73eb557' 
  AND token = 'jJ2/TNRRLy1J0DAcZvaAJfK3280aU/hxDG690TyBLd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}