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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29d0e4012531b1a45b424aba7811bbaa961ca9b7d59c23dd6c5100e02454a42' 
  AND token = 'LxCnoJ6BvfPKwn9nWRPHEhL9JvYh0cmmY0+MBXUL08g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}