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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0ee30f2ab1e0bd2ef83a65ae5caa03e79777c82ee58adc1775afb172a60cd2c' 
  AND token = 'cLzo1eWa7milY5NTB9W2NTTf7kHHrcC5eZ+zv7nQ5oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}