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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80dd2cc180d13d4e2af59cb1ca2d847859f9f9ad8c58666c159f0955bff3403d' 
  AND token = 'cBhlGnADVTs0tZkkhX7n1GEuUjT0gFPBUZbGzYe40tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}