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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed762db5d0a9b06b11bcf561b25a17e718bb667099bfe121a6e54e7a61ad174' 
  AND token = 'gyzE/DEgD6k63NiJ7e4+GzY5ltWrAPsr/h22UZ1Xvo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}