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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fd942352d70765d99b5755e3cc47721c80a5b877b7e38a5e3e88ed513284cf' 
  AND token = '6RBQCLe2HAVVdmQN2pEntL7CeW8JXnE9W7BsIRZ9a4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}