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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe5dbe3e030f38680f1809e51cc82422c6b3ea4f1c0c0f007c0bd9d343c1340' 
  AND token = 'ToiyN79gcxT8SlBGeHNsa6bJjY2PUuZq6huvLj7BsS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}