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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdcd0a0f81f619ac242b9174c73f46b245013f1606527459e6e9602768974075' 
  AND token = '7M8W8gQPf2kkxMwTHiwjPQTByyXb8l8agPmK0aENfnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}