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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a2e2f8c1b67a7ee13de3cd48a110816689cf1227199a9cf39873ad25f12fba' 
  AND token = 'XEfLIO8XVr3NO4Zvffy1dV7+lIQGNbzvQlJPzQ30baA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}