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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d6e032a8ed45495a9cf4fc856cb05a5e936dc9fdbe2a7a01fca1f3222c27af' 
  AND token = '+VEalZI0aKUiiykpKQWMTITgvn9qwjS+1FuxGFz2xVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}