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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b40de16b282a5d9dcf482443d56e0f26ef19853bda081d72df8d4901daae2a35' 
  AND token = 'bqXhLy70N72d0+klgFdkQMq4kt9Wvs2HNSL2acQD7MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}