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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44811d3480d01ba4144c5d5fee9ac7f6ecaf0e4226878582ab15f73d86a7e864' 
  AND token = 'C7QCJ2XAJIwgo84cEYsrRxLHCkqCWP9AVE8s/MDs8Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}