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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d953d5943e45a3014808455be3ad096c6c64f56a21340b77fc5b6e2002381fe' 
  AND token = 'VNStvzkKAo3V3mpUY9xAJFQTkTunm9lxJqelhWeBMbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}