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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd9a8e0aed467d934a4098f27dc530cdcd0d80db8215ada6d40f238d0d6a5f28' 
  AND token = 'U/8BQHy1AbSPVHUmza3LSI5Z0isD7AmhXaNA5bJFq0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}