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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea542b79c384cfd31d1a49096ca22d4ce26999b7f1f3b67d54e61eead345486' 
  AND token = '7JM1o7XDF0GdGAUaWYt3iO99jlPcJ9nTc11VXRrvb+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}