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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '156ac203c89e495d037f112e6acc70a5fbef35570045decce0be9b1c643c5115' 
  AND token = 'WzWqFxEW5AhQwpRIAM4hqPsge9IuAOc+ysklXmI23zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}