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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47d1a1af1a51ec182659e3cccef1b874f5a35c0ea5115ac8a1f9428acddd1964' 
  AND token = 'nA0aa/7CMVRDJeye2t+yYfAiA2zhJRaL0dnF9VeLu7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}