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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea42ac217cd6cb527ea5d9a107a91dcef54062ca41c41759f870002ce952311' 
  AND token = 'LmbtoPm0iiLT7o6AVynTI6HKcFF3Cd2IXc8ItFtWQL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}