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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c7df2e11b6e8e48143965392f5a0c8401343bcc404afc7abf9e85750c2f4f5' 
  AND token = 'L1k1WWqnJdhNMDKBf7hSfDF6HaU1nBacvgfDnrG1Ilk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}