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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05b6e644b89a9e51eca7c002b474b9b4f83c100a174df103520de88b2113e19' 
  AND token = 'QmumA9aHddl+tVcX5/pMmpw8C/kkjpmaBhl3uF1Fxms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}