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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266be9ab9402aec6622987acaedd2eb707f3c2ec4e7c7d5e99da45df62030292' 
  AND token = 'r+d8loFNaoTmpOZEt4O0Ps8KvUCCJE7v9fhpt2Rawdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}