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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b0c353c230f2865331a52ff331becb7b003126f2293f9fd910a7cb8f860482' 
  AND token = 'HkYprE5bs2269ZCKlWzTH3jREaG/+CYF6xxImakVXTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}