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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1884fffc98660a70f062726ac1c1a64fbdf1380b07e31acb0bd71165b9b9e65' 
  AND token = '66U4CmZRy7wH5ONsJB8sM6sWhIL+HK6NvZbdQrxi2sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}