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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88929bf8accf21e46d73a5fd559a84d9ecf22e2b1a109e945129cc81da002b8a' 
  AND token = '5HLT3/abuioCRQoY6D9at0VaRxtliw8vFFbYzVwiiHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}