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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3e142690754f371ab8d5787e9b584c1d7f250b3e88a931ab62f722be70c044' 
  AND token = 'KU98f9WPnD3rn4s9CejkgiEekSEk7u33Ni5cVnlZ0So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}