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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '995aca2be021c4e1cdf86e4ee63896a8775ef06451da502fa4cc5734c6c42cd8' 
  AND token = 'QmY166IZwp1gCP6Dmndzn+4iDg9owTTTJsMLPNSWHTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}