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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e8360ca8c7fea19bbe6c406628a4f8a2f9724b5ba86068f1d8f75d89174e7f' 
  AND token = 'nuvkowa4/PlngfvBQ/2wFw4Q3JSmjOfcctJAya8zMiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}