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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f142a65c74bb40c1234b61b681299005a51a9bff267bcd9f39442c84fce0a9' 
  AND token = '/hbgABeIdRoVNXpAl6+T6R7tJIiHgR3bsv2tOhIGwVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}