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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768defee05e0242e81f277f72f94b559b7ca9ad5b137fbd9e8b50a31abab8ba8' 
  AND token = '1gAWRsEJ9gmXFZeovFX3IuRs0uhITX0wS0WsU8LVy/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}