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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a952a18f944e5d7202d6cdab6aa18517000604bc0c06e6a541e9f6f90da47c' 
  AND token = 'IQDDHd7Uhn2YI3FsFn6bv4agZX9gsWJQXgB+X8l/gD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}