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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03ae1efc87b0177b9f202ce2bd73fdaeb724cbf337dd303bd917c53e2f6deb45' 
  AND token = 'hf1s3vltdixGlI2rPKNZWg27WEOpsyrKTdH3LjvHXkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}