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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c25b1d20e91eac80fd49a2f8be502fb6be00b5e84cdba65ad03301c06d9fe37' 
  AND token = 'HfO3UkhYkG+9H4wxrIddEOKQ5B8nLhB5H+Hg2I9nBN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}