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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7346a49d01f07ebf4e35b069780c93b6b9a14212a4877875ad3ee9b7eb87ed79' 
  AND token = 'TWBoRSjTr542PLJfKtr0P2cYLF2ZbNWVtisMmH5IIeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}