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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0ea2e174ec079edff812c8025a2959b74b960e0ceccc7f66f055f6edef6d2c' 
  AND token = 'H5aqrws1V74S59B1lS+ziT1K/XGhoNcGjgPzqzlrVyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}