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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acf6c78bb7dd2f17694bdc0283a1a5f29a1e759ecbee06fa69ab341133a86f0' 
  AND token = '+oTLzdVLwQVU4t8y24VjstB2eXxGiSLU4KBkS9dcuy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}