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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21faa8573346e0b02086e7371225c71bf04ed3897761c400e5e477731b04dd3f' 
  AND token = 'BJxxVBu73TJ8aT+mtcIORakDBFHq6kFn/Q4nVZ1VRP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}