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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f01859d7c6f06da61f0080ebd87bf556e511ff6beace2c75d53829eccd597b4' 
  AND token = '0RXLb/T1/VS13NaWeGG4aHgkCZsJeyC5zFLmximqVwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}