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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37e17f61504614ec37c6d13abcf478a2544811014a3527500321f5ced9df498' 
  AND token = '5sgltzFIc7Hpn8uMZ7HUXjH05wOAQuHCkJKttLliD2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}